Oral negative-pressure therapy (OPT) provides a non-invasive, mask-free option for obstructive sleep apnea patients with poor CPAP adherence. A meta-analysis of published studies showed a 42.6% reduction in mean apnea–hypopnea index, with a moderate effect size and low heterogeneity, supporting OPT as a potential alternative for selected patients.
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Meta-Analysis Shows Moderate AHI Reduction in OSA
By taevas on 7th Jan 2026
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